Endocrine Abstracts

Introduction: Immune check-point inhibitors (ICI) can cause adverse events in many organs due to the activation of T-cells. Data on the effect of ICI on bones and incidence of fracture is still scarce.Aim: To quantify the rate of osteoporotic fracture before and after the use of ICI in cancer patients.Methods: We retrospectively retrieved pertinent data of all patients who were treated with ICI between 2015 and 2023 at the Tel-Aviv...

Background: True Cushing’s syndrome (CS) is an exceedingly rare condition, thus to avoid unnecessary and costly testing, a diagnostic investigation should only start based on solid clinical suspicion. The current obesity epidemic has become a hurdle in discriminating subjects at real risk for CS from those with the metabolic syndrome. Moreover, many CS patientsrecently diagnosed do not fit the typical clinical profile of ‘at risk subjects’.<p class="abste...